RESEARCH ARTICLE

Evaluation of Salivary C-Reactive Protein in Smokers with Periodontitis in Khartoum state

Anfal Sobhi Mohammed Ahmad.1 Hafsa Ahmed Elrheima Ahmed.2 

• .1BSc, Chemical Pathology department, Faculty of Medical Laboratory Sciences, University of Medical Sciences and Technology, Khartoum 
• .2MSc, Chemical Pathology department., Faculty of Medical Laboratory Sciences, University of Medical Sciences and Technology, Khartoum
•  

Corresponding Author: Hafsa Ahmed Elrheima Ahmed, Chemical Pathology department., Faculty of Medical Laboratory Sciences, University of Medical Sciences and Technology, Khartoum, Sudan. E-mail: [email protected].

Received: May 22, 2024                                                        Published: June 02, 2024

Citation: Hafsa Ahmed Elrheima Ahmed. Evaluation of Salivary C-Reactive Protein in Smokers with Periodontitis in Khartoum state. Int J Complement Intern Med. 2024;6(1):254–258. DOI: 10. 58349/IJCIM. 1. 6. 2024. 00141

Copyright: ©2024 Ahmed. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and build upon your work non-commercially.

Abstract 

Objectives: Smoking widely affects oral health, including its role in the development of periodontitis. C - reactive protein (CRP) is an inflammatory biomarker that can be easily determined in saliva. This study was designed to assess Salivary C-Reactive protein in smokers with periodontitis.

Material and Methods: The study was a prospective cross-sectional study, conducted in Khartoum during the period from January to April 2023. One hundred participants were enrolled in this study, 50of them were cases (cigarette smokers with periodontitis), and the remaining 50 nonsmokers with healthy periodontium as the control group, saliva samples were collected for the assessment of the C reactive protein levels 

Results: Smokers with periodontitis had significantly higher levels of CRP compared to the control group (7.99 ± 0.44 vs 2.38±0.07 mg/L, p=0.000). Additionally, there was no correlation between the level of CRP and the age of the patients (p=0.9, r=0.018). also, no correlation was found between the level of CRP and the duration of smoking (p=0.611, r=0.074). 

Conclusion: There were significant increase in salivary C reactive protein levels among study group, no correlation between age and duration with C reactive protein level 

Keywords: C-reactive protein, periodontitis, saliva, smoking

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