Research Article

Evaluation of Left Ventricular Diastolic and Systolic Functions in Children with Bronchiolitis Followed up at High-Flow Nasal Cannula Oxygen Therapy

Esra Akyüz Özkan.1 İrfan Oğuz Şahin.2 Mahmut Kılıç.3 

• .1Ondokuz Mayıs University Medical Faculty, Department of Pediatrics, Associate Professor Samsun 
• .2Ondokuz Mayıs University Medical Faculty, Department of Pediatric Cardiology Samsun 3Yozgat Bozok University Medical Faculty, Department of Public health, Professor Yozgat
•  

Correspondence: Esra Akyüz Özkan, Department of Pediatrics, Ondokuz Mayıs University Medical Faculty, Department of Pediatrics, Kurupelit Kampüsü, Atakum Samsun, 55139, Turkey, Email [email protected] 

Received: March 20, 2024                                                 Published: March 31, 2024 

Citation: Esra Akyüz. Evaluation of Left Ventricular Diastolic and Systolic Functions in Children with Bronchiolitis Followed up at HighFlow Nasal Cannula Oxygen Therapy. AOJ Emerg and Int Med. 2024;1(2):32–38.

Copyright: ©2024 Özkan. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and build upon your work non-commercially

Abstract 

Background: We aimed to investigate left ventricular (LV) functions in children undergoing high-flow nasal cannula (HFNC) treatment for bronchiolitis and associations between LV functions and vital signs, hemogram and C-reactive protein (CRP) levels. 

Methods: In this prospective study, we enrolled a cohort of 32 patients with bronchiolitis and 36 healthy children between January 2022 and January 2023. Upon admission, we conducted both conventional and tissue Doppler echocardiography assessments to examine the LV systolic and diastolic functions. Vital signs, venous blood gas, hemogram and CRP values were recorded and explored their potential correlations with LV functions. 

Results: While there was no difference in mitral E, A, E/A between the bronchiolitis and control groups, a statistically significant difference was found in mitral E’(p = 0.000), A’(p = 0.000) and E’/A’(p = 0.001). There was no significant difference in the two groups in terms of LV systolic functions. There was a negative correlation with respiratory rate and E/A, Deceleration time (DT), LV Cardiac output (CO) and LV Stroke volume (SV). SpO2 was positively correlated with LV end-systolic volume, LV end-diastolic volume, LV SV and LV CO. Serum platelet level was negatively correlated with E/A, DT, LV SV and LV CO. 

Conclusion: While systolic functions were normal in patients with bronchiolitis, diastolic functions were impaired and this may be due to viral exposure. Notably, as the severity of bronchiolitis increased, a corresponding deterioration in LV functions was observed. Platelet level was inversely proportional to the severity of LV systolic and diastolic functions. 

Keywords: Bronchiolitis, children, high-flow nasal cannula theraphy, left ventricular functions

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